A Connected Jurisdictional Transplant Platform
The Operational Core of Your Transplant System
Transplantation Is Complex and Time-Critical
Every organ offer requires teams to make time-critical decisions using information from multiple organizations and systems. Referrals, donor data, waitlists, allocation policies, laboratory results, logistics, and outcomes all need to come together quickly, yet most transplant technology wasn’t built to support that level of coordination.
Afflo is a real-time organ transplant platform that connects referral, matching, allocation, and outcomes in one system built specifically for transplantation. It works alongside your existing technology to give every team the information they need to make confident decisions.
1 in 5
Recovered organs are not transplanted
Over 100,000 patients are on active waitlists in the US at any given time, and thousands of viable organs go unused each year. The gap between supply and demand makes every decision count.
5 hrs
Average time to process a single referral packet manually
Before a decision can even be made, teams must reconstruct clinical data from fragmented sources, a coordination problem disguised as a workflow.
24/7
Organ offers arrive around the clock, without warning
Deceased-donor decisions happen at any hour under extreme time pressure. Surgeons need the right data immediately.
What Afflo Is
The Operational Core of Your Transplant System
Afflo is the transplant operations platform where your transplant program runs, where referrals are received, patients are managed, organs are matched, logistics are coordinated, devices are deployed, and outcomes are tracked.
Because Afflo sits at the center of your operations, it captures real-time, end-to-end clinical and operational data across the transplant lifecycle that no other system has. That data powers meaningful AI, more accurate reporting, and stronger coordination across your team, partners, and patients.
Afflo brings together more than 250 technical and clinical staff and supports more than 80 customer organizations across the transplant and donation ecosystem in Canada and the United States.
What Makes Afflo Different
Real-Time Data
Every clinical and operational event is captured as it happens, not batched, exported, or delayed.
Purpose-Built
Designed from the ground up for organ donation and transplantation, not adapted from a generic hospital system.
Configurable
Policy rules, allocation logic, and workflows adapt to your jurisdiction without custom code.
Open Platform
Connect Afflo’s AI modules or integrate your transplant center’s own research models.
Modular Adoption
Start with one workflow. Expand as you’re ready. No rip-and-replace required.
From targeted modules to a full system deployment, Afflo integrates seamlessly into your program without requiring you to adapt your operations.
The Transplant Lifecycle
A Truly End-to-End Transplant Platform
Afflo is an end-to-end transplant platform that connects every stage of the transplant journey into one continuous system. Each stage is powerful on its own and exponentially stronger when they work together, creating continuity across the full transplant lifecycle.
Donor Management
Referral capture, deceased and living donor workflows, real-time case status.
Waitlist & Intake
Referral intake, AI-assisted document processing, patient eligibility assessment and waitlist management.
Offer & Decision
Offer screening, AI-assisted organ offer evaluation, hospital-based rules exclusion, local policy.
Matching & Allocation
Policy-driven organ matching and allocation engine, HLA and virtual crossmatch (VXM), and equity-aligned offer ranking.
Logistics & Device Coordination
Organ transport coordination, device deployment and real-time tracking.
Across the Transplant Ecosystem
Built for Every Layer of Transplantation
Transplant Networks
National and regional transplant networks need policy governance, real-time matching, and equitable allocation across every center. Afflo connects stakeholders through a unified platform for organ allocation and policy management. Real-time visibility helps improve coordination across the entire transplant network.
Transplant Programs
Transplant centers need connected, configurable workflows that reduce transplant coordinator burden and support faster, more confident clinical decisions. Afflo supports the entire patient journey, from referral intake and waitlist management to organ allocation, transplantation, and long-term follow-up.
Donor Organizations
Organ procurement organizations (OPOs) and donor organizations need seamless referral capture, interoperability with hospital systems, donor management, and real-time coordination with transplant centers. Afflo connects stakeholders across the organ donation and transplantation process.
Afflo’s Central Hub
Afflo’s model is built on centralized intelligence through the Afflo Central Hub, which connects transplant centers (TXCs) into a unified operational network. Rather than each center managing coordination independently, the Central Hub aggregates real-time data, standardizes workflows, and orchestrates decision-making across all sites.
The result is a more connected, efficient system where complexity is reduced at locally while performance and consistency improve across the entire network.
Platform Capabilities
Afflo automatically ingests referral packets, faxes, PDFs and scanned forms, extracting key clinical, demographic and immunologic data into structured records. Coordinators review and validate rather than transcribe, reducing intake time and errors.
Afflo’s configurable matching engine applies jurisdictional clinical, operational and policy rules to rank candidates and generate offers. Virtual crossmatch at allele, alpha-beta and epitope/eplet resolution provides greater compatibility detail and supports matching for sensitized patients.
When an offer arrives, Afflo brings donor-recipient compatibility and other relevant clinical information into the offer workflow, giving surgeons additional context to support time-critical decisions.
Afflo continuously monitors patient requirements including testing intervals, expiring workups, psychosocial requirements and eligibility status, generating targeted alerts when attention is required. Coordinators spend less time chasing information and more time focused on patients.
Before allocation rules go live, Afflo allows policy teams to test them against historical data to model potential impacts on utilization, equity and outcomes. The Policy Management Workbench makes policy iteration faster, traceable and auditable.
Afflo’s data warehouse turns real-time operational data into dashboards that surface utilization patterns, equity metrics, offer outcomes and coordinator workload. Insights are available within the environment where the work happens.
Built for Transplant and Proven at Scale.
Afflo is chosen by transplant programs and jurisdictional networks because it combines transplant-specific workflows, real-time data, configurable policy and phased implementation in one connected platform. It adapts to local operating models while creating greater consistency across the broader transplant system.
Purpose-Built for Transplant
Every workflow, data model and feature is designed around the realities of transplantation and proven in complex, end-to-end operating environments, including Ontario Health’s Trillium Gift of Life Network, spanning transplant and donor hospitals and HLA laboratories.
Phased, Low-Risk Implementation
Afflo integrates with EHRs, laboratory systems, registries and legacy platforms, allowing your team to continue operating while new capabilities are introduced.
Configurable, Not Customized
Allocation rules, policy logic and workflows are configured to your jurisdiction without custom code, enabling faster implementation and lower long-term cost.
Real-Time
Afflo captures clinical events as they happen. That currency makes AI predictions more meaningful and performance reporting more accurate.
Modular Adoption
Start with one module, whether referral intake, waitlist management or offer analytics, and expand as you’re ready. No big-bang implementation required.
HIPAA & ISO 27001
Enterprise-grade security is built into the platform architecture, not bolted on. Your data is protected at every layer.
Open Platform with Your Models, Our Data and Better Outcomes.
Afflo is designed to be the integration platform for AI in transplant, not just the provider of an AI solution. Because Afflo sits at the operational core, it holds the real-time, end-to-end transactional data that AI models need to deliver meaningful clinical insights. Connect Afflo’s validated models or bring your transplant center’s research models and run them against live data within the workflows where decisions are actually made.
What Afflo Provides
- Secure inference API framework for integrating external AI models
- Configurable UI panels to surface model outputs within live workflows
- Audit-ready logging of every AI-assisted decision
- Data warehouse for model training, validation, and historical simulation
What Your Team Brings
- Institution-specific models trained on your patient populations
- Research models from academic or clinical partnerships
- Jurisdiction-specific allocation optimization algorithms
- Specialty organ models adapted to local practice patterns
- Published research models ready for clinical deployment
The data problem in transplant AI is not a shortage of researchers or algorithms. It is a shortage of real-time, end-to-end operational data. Afflo solves that problem. When your model runs inside Afflo, it runs on the most complete, current transplant data available.
Discover What’s Possible with Afflo
Whether you are modernizing a transplant program or building connected infrastructure across a jurisdiction, we can show you how Afflo can work within your existing environment.