JURISDICTIONAL TRANSPLANT PLATFORM
Every Organ. Every Patient. Every Second.
Why It Matters: The Problem Afflo Solves
Transplantation Is Complex and Time-Critical
Every organ offer requires teams to make time-critical decisions using information from multiple organizations and systems. Referrals, donor data, waitlists, allocation policies, laboratory results, logistics, and outcomes all need to come together quickly, yet most transplant technology wasn't built to support that level of coordination.
Afflo is a real-time transplant platform that connects referral, matching, allocation, and outcomes in one system built specifically for transplantation. It works alongside your existing technology to give every team the information they need to make confident decisions.
1 in 5
Recovered organs are not transplanted
Over 100,000 patients are on active waitlists in the US at any given time, and thousands of viable organs go unused each year. The gap between supply and demand makes every decision count.
5 hrs
Average time to process a single referral packet manually
Before a decision can even be made, teams must reconstruct clinical data from fragmented sources, a coordination problem disguised as a workflow.
24/7
Organ offers arrive around the clock, without warning
Deceased-donor decisions happen at any hour under extreme time pressure. Surgeons need the right data immediately.
WHAT AFFLO IS
The Operational Core of Your Transplant System
Afflo is the transplant operations platform where your transplant program runs, where referrals are received, patients are managed, organs are matched, logistics are coordinated, devices are deployed, and outcomes are tracked.
Since Afflo sits at the center of your operations, it captures real-time, end-to-end clinical and operational data across the transplant lifecycle that no other system has. That data powers meaningful AI, more accurate reporting, and stronger coordination across your team, partners, and patients.
WHAT MAKES AFFLO DIFFERENT
| Real-time data
Every clinical and operational event is captured as it happens, not batched, exported, or delayed
| Purpose-built
Designed from the ground up for transplantation, not adapted from a generic hospital system
| Configurable
Policy rules, allocation logic, and workflows adapt to your jurisdiction without custom code.
| Open platform
Connect Afflo’s AI modules or plug in your transplant center’s own research models.
| Modular adoption
Start with one workflow. Expand as you’re ready. No rip-and-replace required.
From targeted modules to a full system deployment, Afflo integrates seamlessly into your program — without requiring you to adapt your operations.
The Transplant Lifecycle
A Truly End-to-End Transplant Platform
Afflo connects every stage of the transplant journey into one continuous system. Each stage is powerful on its own — and exponentially stronger when they work together.
Donor Management
Referral capture, deceased & living donor workflows, real-time status
Waitlist & Intake
Referral intake, AI document processing, patient eligibility assessment & waitlist management
Matching & Allocation
Policy-driven organ matching and allocation engine, HLA/VXM, equity- aligned offer ranking
Offer & Decision
Offer screening, AI-assisted organ offer evaluation, hospital-based rules exclusion, local policy
Logistics & Device Coordination
Organ transport coordination, device deployment, real-time tracking
Who We Serve
Built for Every Layer of Transplantation
Transplant Networks
National and regional networks need policy governance, real-time matching, and equitable allocation across every center. Afflo connects stakeholders through a unified platform for organ allocation and policy management. Real-time visibility helps improve coordination across the entire transplant network.
Transplant Programs
Transplant centers need connected, configurable workflows that reduce transplant coordinator burden and support faster, more confident clinical decisions. Afflo supports the entire patient journey, from referral intake and waitlist management to organ allocation, transplantation, and long-term follow-up.
Donor Organizations
OPOs and donor organizations need seamless referral capture, interoperability with hospital systems, donor management, and real-time coordination with transplant centers. Afflo connects stakeholders across the organ donation and transplantation process.
Platform Capabilities
Afflo’s model is built on centralized intelligence through the Afflo Central Hub, which connects transplant centers (TXCs) into a unified operational network. Rather than each center managing coordination independently, the Central Hub aggregates real-time data, standardizes workflows, and orchestrates decision-making across all sites.
The result is a more connected, efficient system where complexity is reduced at locally while performance and consistency improve across the entire network.
Intelligent Document & Referral Intake
Afflo automatically ingests referral packets, faxes, PDFs, and scanned forms, extracting key clinical, demographic, and immunologic data into structured records. Coordinators review and validate rather than transcribe, significantly reducing intake time and errors.
Waitlist Intelligence & Risk Monitoring
Afflo continuously monitors every patient, including testing intervals, expiring workups, psychosocial requirements, and eligibility status, generating targeted alerts before problems occur. Coordinators spend less time chasing information and more time caring for patients.
Policy-Driven Matching & Allocation
Afflo's configurable matching engine applies your jurisdiction's clinical, operational, and policy rules to rank candidates and generate offers. Virtual crossmatch at allele, alpha-beta, and epitope/eplet resolution improves match quality and expands access for sensitized patients.
Policy Simulation & Governance
Before allocation rules go live, Afflo lets policy teams test them against historical data to model their impact on utilization, equity, and outcomes. The Policy Management Workbench makes policy iteration faster, auditable, and safe.
Organ Offer Decision Support
When an offer arrives, Afflo's AI surfaces donor-recipient compatibility, predicted graft survival, and estimated time to the next comparable offer, giving surgeons the quantitative context they need to make faster, more consistent decisions.
Performance Insights & Analytics
Afflo's data warehouse turns real-time operational data into dashboards that surface utilization patterns, equity metrics, offer outcomes, and coordinator workload. No data export required. Insights are available where the work happens.
Why Transplant Programs Choose Afflo
Purpose-Built for Transplant
Every workflow, data model, and feature was designed around the realities of transplantation, not adapted from a generic hospital system.
Modular Adoption
Start with one module, whether referral intake, waitlist management, or offer analytics, and expand as you're ready. No big-bang implementation required.
Real-Time
Afflo captures clinical events as they happen. That currency makes AI predictions more meaningful and performance reporting more accurate.
HIPAA & ISO 27001
Enterprise-grade security is built into the platform architecture, not bolted on. Your data is protected at every layer.
Configurable, Not Customized
Allocation rules, policy logic, and workflows are configured to your jurisdiction without custom code, enabling faster implementation and lower long-term cost.
Phased, Low-Risk Implementation
Afflo integrates with EMRs, laboratory systems, registries, and legacy platforms, allowing your team to continue operating while new capabilities are introduced.
OPEN PLATFORM
YOUR MODELS. OUR DATA. BETTER OUTCOMES.
Afflo is designed to be the integration platform for AI in transplant, not just the provider of an AI solution. Because Afflo sits at the operational core, it holds the real-time, end-to-end transactional data that AI models need to deliver meaningful clinical insights. Connect Afflo’s validated models or bring your transplant center’s research models and run them against live data within the workflows where decisions are actually made.
What Afflo Provides
→ Real-time transactional data across the full transplant lifecycle
→ Secure inference API framework for plugging in external AI models
→ Configurable UI panels to surface model outputs within live workflows
→ Audit-ready logging of every AI- assisted decision
→ Data warehouse for model training, validation, and historical simulation
What Your Team Brings
→ Institution-specific models trained on your patient populations
→ Research models from academic or clinical partnerships
→ Jurisdiction-specific allocation optimization algorithms
→ Specialty organ models adapted to local practice patterns
→ Published research models ready for clinical deployment
The data problem in transplant AI is not a shortage of researchers or algorithms. It is a shortage of real-time, end-to-end operational data. Afflo solves that problem. When your model runs inside Afflo, it runs on the most complete, current transplant data available.
Discover What’s Possible with Afflo
Ready to modernize your transplant system? Let's talk.