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Your Questions About Afflo, Answered

Afflo is a modular transplant software platform built to simplify organ transplant operations. These FAQs answer common questions about how Afflo supports organ donation and transplantation, including allocation, patient and donor management, AI-assisted workflows, integration, security and performance.

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Frequently Asked Questions

General Questions

Afflo is a comprehensive, modular software platform designed specifically for organ donation and transplantation. It combines real-time allocation, policy management, AI-assisted workflows, donor and patient tracking and operational coordination to improve outcomes, reduce administrative burden and support transparency and equity.

Afflo was built from the ground up for transplantation. It handles complex, time-sensitive workflows, high-volume offers, multi-organ matching and policy changes while integrating seamlessly with existing clinical, administrative and laboratory systems.

Afflo provides the technology infrastructure behind key Buckeye solutions. Buckeye’s broad transplant operations network also gives Afflo ongoing exposure to real-world workflows and operating requirements, helping inform the continued development of the platform.

Afflo captures data, preserves decision logic and provides analytics to evaluate allocation outcomes across demographic, geographic and clinical dimensions. Policy simulation tools allow teams to test proposed changes before deployment and assess potential impacts on equity, utilization and other defined measures.

Yes. Afflo can be configured for local, regional or national transplant policies. Allocation rules, ranking logic, exclusion criteria and workflows can be configured to the requirements of different programs and jurisdictions, while modular deployment allows capabilities to be introduced in phases.

Afflo currently manages more than 800 clinical allocation rules, reducing the time required to update, test and release rule changes from months to days.

Afflo uses enterprise-grade encryption, role-based access controls and audit logging to protect sensitive patient and operational data. ISO 27001 and HIPAA certification support security and governance across Afflo workflows and integrations.

Afflo connects with EHRs, laboratory systems, registries and other clinical and operational systems using standards-based integration. Afflo supports bidirectional EHR integration using HL7 and FHIR, with connections to laboratory, imaging, referral and HLA data sources.

AI & Workflows

Afflo AI is designed specifically for transplantation. It uses connected, real-time transplant data to structure complex information, automate routine tasks, track patient and donor status and highlight high-priority actions, helping teams work more efficiently and make faster, more confident decisions.

Afflo connects data generated across referral, patient and donor management, matching, allocation, offers, logistics and outcomes. Because that information remains connected across the transplant journey, analytical and AI models can operate with current clinical and operational context rather than relying solely on disconnected data exports.

Afflo’s underlying transplant data infrastructure already supports high-volume automated decision workflows.

Afflo extracts and standardizes information from referral packets, laboratory results, consult notes and connected systems, converting relevant information into structured records for review and validation. This reduces manual work and gives teams more usable data within the transplant workflow.

Yes. Afflo AI evaluates donor and recipient data in real time, highlighting compatibility, clinical criteria, risk factors and anomalies. This gives transplant teams additional context to evaluate organ offers and make time-critical decisions.

Afflo tracks testing intervals, requirements, checklist progress, status changes and key deadlines. AI-generated alerts and risk indicators help teams identify patients who require attention and reduce avoidable delays.

Afflo incorporates transport timelines, routing and scheduling data into the broader transplant workflow to support organ movement and coordination across transplant centers and procurement teams.

Yes. AI works with Afflo’s policy-native design to reflect updated allocation rules, ranking logic and exclusion criteria without disrupting live operations.

Coordinators, surgeons, OPO staff, laboratories and other authorized team members can work through structured workflows, shared notifications and role-based access so relevant information stays connected and teams remain aligned.

The platform tracks outcomes, captures structured data and provides analytics to measure performance, test new approaches and optimize workflows over time.

Performance & Outcomes

Afflo provides actionable insights into referrals, consents, organ utilization, patient progression and transplant outcomes. Teams can identify trends, evaluate interventions and make evidence-based improvements.

Afflo supports phased deployment. Organizations can begin with individual modules or defined workflows, integrate them into live operations and expand over time based on priorities and implementation requirements.

By automating data capture, standardizing workflows and providing AI-assisted alerts, Afflo reduces repetitive manual work so teams can spend more time on patient care and critical decision-making.

Access is controlled through role-based permissions. Users see the data, workflows and alerts appropriate to their responsibilities, helping maintain privacy while supporting coordination across authorized teams.

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Want to Know More?

Have a question about Afflo, your transplant environment or a specific platform capability? Talk with our team about how Afflo can support your organization.

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