A connected organ allocation platform for national and regional transplant networks, helping streamline allocation, strengthen oversight and improve access to transplants.
Transparent, Accountable Allocation at National Scale
A jurisdictional transplant network is not a bigger transplant center. It’s a different problem entirely. Thousands of concurrent match runs. Dozens of policies that change as clinical evidence evolves. Equity requirements that span geographies and demographics. Offers that must move in minutes, not hours.
Afflo is built specifically for this layer of transplantation: the network itself.
Afflo Central Hub connects transplant centers (TXCs) into a unified operational network, aggregating real-time data, standardizing workflows and coordinating decision-making across participating sites.
Afflo supports a jurisdiction-wide operating environment connecting one coordinating body, eight transplant hospitals and four HLA laboratory services, supporting hundreds of physicians, nurses and transplant coordinators.
Afflo gives transplant networks the infrastructure to govern policy, drive equity and answer to every stakeholder with confidence. You can align stakeholders across your transplant network.
Organ Allocation Infrastructure Built for Scale
Afflo unifies matching logic, policy configuration, immunologic precision and offers coordination in one operational system built for high-volume organ allocation. It supports live offer execution while preserving the governance, equity and speed required at network scale.
Fewer Non-Productive Offers, Faster Offer Completion
Afflo reduces non-productive offers by improving match quality before an offer is sent. The allocation engine applies clinical, operational and policy-specific constraints to produce offers with higher relevance and complete context from the outset.
Reduce offer churn and unnecessary declines
Run parallel, automated offer cycles across channels
Deliver complete context earlier to decision-makers
Keep organs moving when primary offers are declined
THE RESULT
Faster decisions and better utilization
across the network.
Policy Management Designed for Continuous Evolution
Organ allocation policies evolve as clinical evidence, priorities and operating requirements change. Afflo’s Policy Management Workbench lets jurisdictional teams configure, test, update and govern matching and allocation logic directly, without heavy IT involvement.
Continuous Distribution Frameworks
Apply allocation rules across the waitlist without relying on rigid categories.
Category-Based and Hybrid Ranking Models
Support both traditional and flexible ranking approaches to match policy and clinical priorities.
Center- and Geography-Specific Rollout Strategies
Tailor policy updates by center or region, implementing changes while minimizing disruption.
Incremental Adoption by Organ Type or Phase
Introduce changes step by step for specific organs or rollout phases.
Networks move faster while maintaining full oversight and accountability.
High-Resolution Virtual Crossmatch That Expands Access
Afflo’s virtual crossmatch engine operates at high immunologic resolution, including:
- Allele-specific typing
- Alpha-beta HLA interpretation
- Epitope and eplet-level policy support
- Highly sensitized patient optimization
This precision improves match confidence, reduces unexpected positive crossmatches and expands access for harder-to-place patients.
For distance placements, high-resolution VXM is especially critical, reducing discards and negative outcomes where time and travel amplify risk.
Afflo reports approximately 255,000 digital HLA crossmatches annually, with individual digital crossmatches running in seconds.
Afflo lets transplant networks test policy changes before they go live, not after.
Policy Forge
Manage exclusion, ranking and decline logic without operational disruption.
Policy Time Machine
Simulate policy changes against historical allocation data to confirm expected outcomes and surface unintended consequences before going live.
The Result
Your organisation will benefit from faster iteration, lower implementation risk and stronger governance.
Audit-Ready Allocation Documentation and Governance
Afflo captures allocation logic and policy configuration in a structured, documentation-ready format. Rule tracking and data dictionaries support:
- Audit readiness and regulatory compliance
- Transparent governance across jurisdictions
- Knowledge transfer and operational continuity
- Continuous improvement without losing accountability
Network Effects That Strengthen Every Center
Afflo gives transplant networks shared operational learning at scale. Consistent workflows, shared allocation infrastructure and real-time visibility help networks operationalize best practices across every center.
Streamlined coordination across all stakeholders
Faster alignment across jurisdictions and centers
Shared learnings from live allocation performance
System-wide improvement that benefits every participant
THE RESULT
When allocation improves for one center,
the entire network becomes stronger.
Ready to Build Stronger Allocation Infrastructure?
Book a 30-minute demo and see how Afflo supports real-time matching, policy governance and equity-aligned allocation across your jurisdiction.